SCHEMBL21816850

SCHEMBL21816850

Nc1ccc(N=Nc2ccc(CC=O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.58
▸ MEN1 O00255 4/20 0.58
▸ KMT2A Q03164 4/20 0.58
▸ TDP1 Q9NUW8 4/20 0.58
▸ RAB9A P51151 3/20 0.58
▸ NPC1 O15118 2/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ PKM P14618 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ CA12 O43570 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ CA9 Q16790 2/20 0.47
▸ CYP3A4 P08684 2/20 0.41
▸ TSHR P16473 2/20 0.41
▸ GFER P55789 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ LOXL2 Q9Y4K0 1/20 0.39
▸ MAOB P27338 3/20 0.35
▸ MAOA P21397 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076722 0.89 CYP3A4 (0.39) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL721540 0.87 ALDH1A1 (0.52) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL9611208 0.78 MAPT (0.70) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL20251147 0.78 MAPT (0.70) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL18826101 0.78 MAPT (0.70) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL20251154 0.78 MAPT (0.70) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL11329226 0.76 MAPT (1.00) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL16556 0.76 MAPT (1.00) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL205992 0.76 MAPT (1.00) MAPTMEN1KMT2ATDP1RAB9A
SCHEMBL11329238 0.76 MAPT (1.00) MAPTMEN1KMT2ATDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856887-A1 BIOREACTOR AND METHOD FOR CULTIVATING BIOLOGICAL CELLS ON SUBSTRATE FILAMENTS FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2021-08-04 — — EP disclosed
WO-2020064639-A1 BIOREACTOR AND METHOD FOR CULTIVATING BIOLOGICAL CELLS ON SUBSTRATE FILAMENTS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2020-04-02 — — WO disclosed
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