Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21817806 | 1.00 | WDR5 (0.78) | WDR5KMT2A | |
| SCHEMBL21817116 | 0.94 | WDR5 (0.78) | WDR5KMT2A | |
| SCHEMBL21817115 | 0.94 | WDR5 (0.78) | WDR5KMT2A | |
| SCHEMBL21859191 | 0.91 | WDR5 (0.74) | WDR5KMT2A | |
| SCHEMBL30002720 | 0.88 | WDR5 (1.00) | WDR5KMT2A | |
| SCHEMBL21817768 | 0.88 | WDR5 (1.00) | WDR5KMT2A | |
| SCHEMBL21817382 | 0.82 | WDR5 (0.90) | WDR5KMT2A | |
| SCHEMBL21711928 | 0.80 | WDR5 (0.70) | WDR5KMT2A | |
| SCHEMBL21711599 | 0.80 | WDR5 (0.76) | WDR5KMT2A | |
| SCHEMBL21711605 | 0.80 | WDR5 (0.69) | WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844044-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-11-24 | — | — | US | claimed |
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-04-02 | — | — | US | claimed |
| US-10844044-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | WDR5 1/4885KMT2A 238/4885 |
| US-10844044-B2 | WDR5 inhibitors and modulators | WDR5, WDR1, WDR3 | WDR5 1/4885KMT2A 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.