SCHEMBL21820174

SCHEMBL21820174

CC(C)(C)c1ccc(OS(=O)(=O)c2cccc3c2C=CC(=[N+]=[N-])C3=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
PLA2G1B P04054 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATG4B Q9Y4P1 2/20 0.35
KDM4E B2RXH2 2/20 0.35
KDM4A O75164 1/20 0.35
APEX1 P27695 1/20 0.34
ENPP1 P22413 5/20 0.33
ENPP3 O14638 4/20 0.33
HPGD P15428 2/20 0.32
USP2 O75604 1/20 0.32
CXCR5 P32302 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17227799 0.90
SCHEMBL11973356 0.90 NR3C2 (0.33) ALDH1A1MEN1KMT2AKDM4ENPC1
SCHEMBL13155956 0.90 LMNA (0.32) MEN1KMT2ANPC1RAB9ASENP8
SCHEMBL11972854 0.89 CYP3A4 (0.34) SMN1; SMN2
SCHEMBL3152091 0.89
SCHEMBL3154832 0.89
SCHEMBL17054255 0.88 CA1 (0.35) CA1CA2CA9ALDH1A1MAPT
SCHEMBL12780179 0.87 LMNA (0.36) CA1CA2CA9ALDH1A1MAPT
SCHEMBL3155832 0.86
SCHEMBL15334630 0.85 ENPP1 (0.30) ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11049812-B2 Semiconductor devices and methods of forming the same TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2021-06-29 US disclosed
US-20200286832-A1 SEMICONDCUTOR DEVICES AND METHODS OF FORMING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-09-10 US disclosed
US-10665545-B2 Semiconductor devices, semiconductor packages and methods of forming the same TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-05-26 US disclosed
US-20200091073-A1 SEMICONDCUTOR DEVICES, SEMICONDCUTOR PACKAGES AND METHODS OF FORMING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2020-03-19 US disclosed