Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821307 | 0.90 | SMN1; SMN2 (0.48) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL21821305 | 0.90 | SMN1; SMN2 (0.48) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL30645019 | 0.87 | NPC1 (0.47) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL20743761 | 0.87 | NPC1 (0.47) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL28531797 | 0.86 | ITGA5 (0.42) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL28531799 | 0.86 | ITGA5 (0.42) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL19283490 | 0.86 | ITGA5 (0.45) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL21821310 | 0.86 | ITGA5 (0.45) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL19283613 | 0.86 | ITGB6 (0.55) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 | |
| SCHEMBL19301055 | 0.86 | ITGA5 (0.47) | ITGA5ITGB6ITGB8SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419973-B1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2020-04-08 | — | — | EP | disclosed |