Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 11/20 | 0.80 |
| ▸ | CCR2 | P41597 | 8/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31689652 | 1.00 | CCR9 (0.80) | CCR9CCR2PPARG | |
| SCHEMBL21822218 | 0.85 | CCR9 (0.62) | CCR9CCR2PPARG | |
| SCHEMBL28593764 | 0.84 | CCR9 (0.72) | CCR9CCR2 | |
| SCHEMBL21822376 | 0.83 | CCR9 (0.71) | CCR9CCR2 | |
| SCHEMBL31689702 | 0.83 | CCR9 (0.71) | CCR9CCR2 | |
| SCHEMBL21822522 | 0.83 | CCR9 (0.56) | CCR9CCR2PPARG | |
| SCHEMBL31689672 | 0.83 | CCR9 (0.56) | CCR9CCR2PPARG | |
| SCHEMBL31689688 | 0.81 | CCR9 (0.69) | CCR9CCR2 | |
| SCHEMBL21822281 | 0.81 | CCR9 (0.69) | CCR9CCR2 | |
| SCHEMBL21822721 | 0.81 | CCR9 (0.68) | CCR9CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | Disc Medicine, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2020072580-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. (US) | 2020-04-09 | — | — | WO | disclosed |