Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 11/20 | 0.80 |
| ▸ | CCR2 | P41597 | 8/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822129 | 1.00 | CCR9 (0.80) | CCR9CCR2PPARG | |
| SCHEMBL21822218 | 0.85 | CCR9 (0.62) | CCR9CCR2PPARG | |
| SCHEMBL28593764 | 0.84 | CCR9 (0.72) | CCR9CCR2 | |
| SCHEMBL21822376 | 0.83 | CCR9 (0.71) | CCR9CCR2 | |
| SCHEMBL31689702 | 0.83 | CCR9 (0.71) | CCR9CCR2 | |
| SCHEMBL21822522 | 0.83 | CCR9 (0.56) | CCR9CCR2PPARG | |
| SCHEMBL31689672 | 0.83 | CCR9 (0.56) | CCR9CCR2PPARG | |
| SCHEMBL31689688 | 0.81 | CCR9 (0.69) | CCR9CCR2 | |
| SCHEMBL21822281 | 0.81 | CCR9 (0.69) | CCR9CCR2 | |
| SCHEMBL21822721 | 0.81 | CCR9 (0.68) | CCR9CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428415-B2 | Matriptase 2 inhibitors and uses thereof | DISC MEDICINE, INC. (US) | 2025-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428415-B2 | Matriptase 2 inhibitors and uses thereof | MMP7, MATR3, SPINT2 | CCR9 2381/4885CCR2 2671/4885PPARG 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.