Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31689691 | 0.90 | CCR9 (0.55) | CCR9CNR1F10CNR2MEN1 | |
| SCHEMBL21822131 | 0.90 | CCR9 (0.55) | CCR9CNR1F10CNR2MEN1 | |
| SCHEMBL28580764 | 0.89 | CCR9 (0.48) | CCR9CNR1F10CNR2MEN1 | |
| SCHEMBL21822341 | 0.85 | F10 (0.49) | CNR1F10CNR2MEN1NPC1 | |
| SCHEMBL28915335 | 0.84 | F10 (0.43) | CNR1F10CNR2MEN1NPC1 | |
| SCHEMBL21822432 | 0.83 | F10 (0.42) | CNR1F10CNR2MEN1NPC1 | |
| SCHEMBL28573653 | 0.79 | CCR9 (0.54) | CCR9CNR1F10KMT2APRKAA2 | |
| SCHEMBL31689641 | 0.79 | CCR9 (0.54) | CCR9CNR1F10KMT2APRKAA2 | |
| SCHEMBL28573651 | 0.79 | CCR9 (0.54) | CCR9CNR1F10KMT2APRKAA2 | |
| SCHEMBL28588625 | 0.78 | CCR9 (0.49) | CCR9CNR1F10PRKAA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | Disc Medicine, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2020072580-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. (US) | 2020-04-09 | — | — | WO | disclosed |