Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31689691 | 0.91 | CCR9 (0.55) | CCR9F10CNR1CNR2MEN1 | |
| SCHEMBL21822131 | 0.91 | CCR9 (0.55) | CCR9F10CNR1CNR2MEN1 | |
| SCHEMBL28588621 | 0.89 | CCR9 (0.49) | CCR9F10CNR1LMNAKDM4E | |
| SCHEMBL28588625 | 0.89 | CCR9 (0.49) | CCR9F10CNR1LMNAKDM4E | |
| SCHEMBL21822242 | 0.89 | CCR9 (0.48) | CCR9F10CNR1CNR2MEN1 | |
| SCHEMBL21822590 | 0.82 | CCR9 (0.48) | CCR9F10CNR1KMT2ALMNA | |
| SCHEMBL28573651 | 0.81 | CCR9 (0.54) | CCR9F10CNR1KMT2APRKAA2 | |
| SCHEMBL28573653 | 0.81 | CCR9 (0.54) | CCR9F10CNR1KMT2APRKAA2 | |
| SCHEMBL31689641 | 0.81 | CCR9 (0.54) | CCR9F10CNR1KMT2APRKAA2 | |
| SCHEMBL28573701 | 0.81 | CNR1 (0.45) | CCR9F10CNR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |