Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 7/20 | 0.53 |
| ▸ | ACACB | O00763 | 8/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10257014 | 1.00 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL2943924 | 1.00 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL21823937 | 1.00 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL2943925 | 1.00 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL16982762 | 0.91 | ACACA (0.44) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL2136278 | 0.90 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL21823941 | 0.90 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL2136283 | 0.90 | ACACA (0.53) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL21823817 | 0.88 | CACNA1I (0.55) | ACACAACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL2944178 | 0.88 | CACNA1I (0.55) | ACACAACACBCACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |