Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | STAT3 | P40763 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143516 | 0.85 | MEN1 (0.89) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL14132905 | 0.85 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL15173711 | 0.80 | SMN1; SMN2 (0.67) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL23297235 | 0.80 | MEN1 (0.72) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL23297349 | 0.80 | MEN1 (0.72) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL2341868 | 0.78 | TSHR (0.64) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL22632858 | 0.77 | POLB (0.78) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL2321371 | 0.75 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL10047706 | 0.75 | POLB (0.65) | MAPTSMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL8041029 | 0.74 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | MAPT 4500/4885SMN1; SMN2 3894/4885MEN1 1211/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | MAPT 4500/4885SMN1; SMN2 3894/4885MEN1 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.