Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | STAT3 | P40763 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15173711 | 0.87 | SMN1; SMN2 (0.67) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL13273519 | 0.84 | SMN1; SMN2 (0.51) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL2411656 | 0.80 | MEN1 (0.58) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL2182531 | 0.78 | MAPT (1.00) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL1143516 | 0.77 | MEN1 (0.89) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL27667670 | 0.77 | TSHR (0.47) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL27647109 | 0.76 | TLR8 (0.55) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL14132905 | 0.74 | SMN1; SMN2 (1.00) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL18003909 | 0.73 | SMN1; SMN2 (0.61) | TSHRPOLBLMNANPC1RAB9A | |
| SCHEMBL8041065 | 0.72 | ALDH1A1 (0.48) | TSHRPOLBLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |