Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 19/20 | 0.90 |
| ▸ | ITGB6 | P18564 | 16/20 | 0.90 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.65 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.65 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.65 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21825702 | 1.00 | ITGAV (0.90) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21825709 | 0.95 | ITGAV (1.00) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21825708 | 0.95 | ITGAV (1.00) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL31124981 | 0.95 | ITGAV (1.00) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21825952 | 0.95 | ITGAV (1.00) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21826085 | 0.90 | ITGAV (0.90) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21826062 | 0.90 | ITGAV (0.78) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21825903 | 0.90 | ITGAV (0.90) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21826414 | 0.90 | ITGAV (0.90) | ITGAVITGB6ITGB1ITGB3ITGA4 | |
| SCHEMBL21826058 | 0.90 | ITGAV (0.78) | ITGAVITGB6ITGB1ITGB3ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195053-B | Amino acid compounds and methods of use | 普利安特治疗公司 | 2024-08-30 | — | — | CN | claimed |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | claimed |
| CN-113195053-B | Amino acid compounds and methods of use | 普利安特治疗公司 | 2024-08-30 | — | — | CN | disclosed |
| US-20240270742-A1 | SUBSTITUTED AMINO ACIDS AS INTEGRIN INHIBITORS | PLIANT THERAPEUTICS INC (US) | 2024-08-15 | — | — | US | disclosed |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2022-05-12 | — | — | US | disclosed |
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2022-05-12 | — | — | US | disclosed |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| CN-113195053-A | Amino acid compounds and methods of use | 普利安特治疗公司 | 2021-07-30 | — | — | CN | disclosed |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2020-04-09 | — | — | US | disclosed |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2020-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA1, ITGAL | ITGAV 6/4885ITGB6 1/4885ITGB1 4/4885 |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA1, ITGAL | ITGAV 6/4885ITGB6 1/4885ITGB1 4/4885 |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | ITGB6, ITGA1, ITGB1 | ITGAV 4/4885ITGB6 1/4885ITGB1 3/4885 |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | ITGB6, ITGA1, ITGB1 | ITGAV 4/4885ITGB6 1/4885ITGB1 3/4885 |
| US-20240270742-A1 | SUBSTITUTED AMINO ACIDS AS INTEGRIN INHIBITORS | ITGB6, ITGA1, ITGB1 | ITGAV 4/4885ITGB6 1/4885ITGB1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.