ITGA1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL7577795	0.74	4/20
SCHEMBL6204782	0.69	4/20
SCHEMBL6207007	0.69	4/20
SCHEMBL6207012	0.69	4/20
SCHEMBL2029062	0.68	4/20
SCHEMBL4815316	0.67	4/20
SCHEMBL94831	0.62	4/20
SCHEMBL3267231	0.61	4/20
SCHEMBL4804704	0.60	4/20
SCHEMBL3268657	0.59	4/20
SCHEMBL3267463	0.59	4/20
SCHEMBL4882914	0.59	4/20
SCHEMBL4875332	0.59	4/20
SCHEMBL7588364	0.58	4/20
SCHEMBL4880800	0.58	4/20
SCHEMBL5020767	0.57	4/20
SCHEMBL2158700	0.56	4/20
SCHEMBL4650569	0.55	4/20
SCHEMBL2372252	0.55	4/20
SCHEMBL7577319	0.55	4/20

Clinical trials — most relevant to ITGA1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Crohn's Disease	PHASE2	RECRUITING
Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Ulcerative Colitis	PHASE2	RECRUITING
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Angiogenesis in Ischemic Heart Disease	PHASE2	UNKNOWN
A Gene Therapy Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I	PHASE1	WITHDRAWN
Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors	PHASE1	COMPLETED
Vedolizumab (Anti-alpha4beta7) in Subjects With HIV Infection Undergoing Analytical Treatment Interruption	PHASE1	COMPLETED
68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis	EARLY_PHASE1	UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Patients With Rheumatoid Arthritis	EARLY_PHASE1	UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma	EARLY_PHASE1	UNKNOWN
An Open-label, Single-arm, Single-center Study to Evaluate the Diagnostic Efficacy of a Novel PET Probe, 68Ga-SFB6-ZN01, in Patients With Malignant Tumors	EARLY_PHASE1	NOT_YET_RECRUITING
68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients	EARLY_PHASE1	UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Stroke	EARLY_PHASE1	UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Myocardial Infarction	EARLY_PHASE1	UNKNOWN
Angiogenesis and Fibrosis in Aortic Stenosis	nan	COMPLETED
Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS)	nan	COMPLETED
Angiogenesis and Fibrosis in Myocardial Infarction	nan	COMPLETED
Clinical Study of 18F-FAPI-RGD in Ovarian Cancer	nan	COMPLETED
The Role of CD4+ T Cell Subsets in the Mechanism of Action of Vedolizumab in Ulcerative Colitis	nan	UNKNOWN
Levels of Circulating T Cells Expressing VLA-1 Collagen Receptors	nan	COMPLETED
The Role of Platelet Surface α2β1 Integrin Expression as a Risk Factor in Thrombotic and/or Bleeding Complications	nan	COMPLETED
Eosinophil β1 Integrin Activation as a Biomarker for Eosinophilic Esophagitis	nan	COMPLETED
Role of CD11a in Pathogenesis of Primary ITP and Effect of Immunosuppressive Therapy on Its Level	nan	COMPLETED
Markers of Vascular Calcification in Diabetic Nephropathy in Patients With Diabetic Nephropathy	nan	UNKNOWN
ITGA2b and SELP Expression in Cancer Pancreas and Biliary Tract Cancer	nan	UNKNOWN
The Role of the Novel 99mTc-NC100692 Tracer in Patients at High Risk or Known Breast Cancer	nan	UNKNOWN
Hypolipemic Treatment in Acute Coronary Syndrome (ACS): Antithrombotic Effects	nan	UNKNOWN
IMaging Pilot Study of the αvβ6 Integrin Radiotracer [18F]-A20FMDV2 in PAtients With Solid Cancer Types	nan	COMPLETED
Performance of 177Lu-PSMA-I&T for RLT in mCRPC - Prospective Multicenter Swiss Registry Study	nan	COMPLETED
Clinical Study of 18F-FAPI-RGD in Breast Tumors	nan	COMPLETED
Early Regenerative Intervention for Post-Traumatic Osteoarthritis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a ITGA1 binder may also engage these)

Protein	Name	Similarity
P18614	—	1.000	P18614 →
Q3V3R4	—	0.998	Q3V3R4 →
P26009	—	0.962	P26009 →
ITGB8	Integrin beta-8	0.962	landscape →
Q62469	—	0.962	Q62469 →
Q9HCM2	—	0.958	Q9HCM2 →
Q13797	—	0.957	Q13797 →
B8JK39	—	0.956	B8JK39 →
Q8BFR2	—	0.956	Q8BFR2 →
P26013	—	0.955	P26013 →
Q0VBD0	—	0.955	Q0VBD0 →
ITGA2	Integrin alpha-2	0.954	landscape →
Q80UG2	—	0.953	Q80UG2 →
O75051	—	0.953	O75051 →
P53710	—	0.952	P53710 →
Q8N475	—	0.952	Q8N475 →
Q99J86	—	0.951	Q99J86 →
ITGA4	Integrin alpha-4	0.950	landscape →
O70309	—	0.950	O70309 →
Q90615	—	0.949	Q90615 →
ITGA8	Integrin alpha-8 [Cleaved into: Integrin alph	0.949	landscape →
ITGB5	Integrin beta-5	0.949	landscape →
P70207	—	0.949	P70207 →
ITGB3	Integrin beta-3	0.948	landscape →
Q9JIA1	—	0.947	Q9JIA1 →
Q5E9T6	—	0.947	Q5E9T6 →
Q1EGL2	—	0.947	Q1EGL2 →
Q8K4Y5	—	0.947	Q8K4Y5 →
P39038	—	0.946	P39038 →
Q6QNK2	—	0.946	Q6QNK2 →