SCHEMBL2182662

SCHEMBL2182662

CC(C)C[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@H]([C]=O)CCCNC(=N)N

nearest known ligand 0.70

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 19/20 0.70
NPY1R P25929 12/20 0.70
NPY5R Q15761 10/20 0.70
NPY2R P49146 8/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30381408 0.86 NPY4R (0.75) NPY4RNPY1RNPY5RNPY2R
SCHEMBL20630942 0.86 NPY4R (0.78) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29901565 0.85 NPY4R (0.73) NPY4RNPY1RNPY5RNPY2R
SCHEMBL1552144 0.84 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31666017 0.84 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29901561 0.84 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30849955 0.83 NPY4R (0.76) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30804481 0.83 NPY4R (0.76) NPY4RNPY1RNPY5RNPY2R
SCHEMBL11098504 0.83 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL2194066 0.83 NPY4R (0.63) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP NPY4R 567/4885NPY1R 544/4885NPY5R 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.