Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813536 | 1.00 | DPP4 (0.33) | DPP4PREPDPP8DPP9 | |
| SCHEMBL28244561 | 1.00 | DPP4 (0.33) | DPP4PREPDPP8DPP9 | |
| SCHEMBL22311138 | 0.80 | CCNE1 (0.32) | — | |
| SCHEMBL21813562 | 0.80 | CCNE1 (0.32) | — | |
| SCHEMBL21828473 | 0.80 | CCNE1 (0.32) | — | |
| SCHEMBL22689356 | 0.77 | DPP4 (0.38) | DPP4PREPDPP8DPP9 | |
| SCHEMBL7127 | 0.77 | DPP4 (0.38) | DPP4PREPDPP8DPP9 | |
| SCHEMBL21408141 | 0.73 | MAPT (0.37) | — | |
| SCHEMBL29183838 | 0.71 | POLB (0.35) | — | |
| SCHEMBL25254512 | 0.71 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861000-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE | Genzyme Corporation (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072504-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE | GENZYME CORPORATION (US) | 2020-04-09 | — | — | WO | disclosed |
| CN-104918615-B | The method for treating hepatopathy | 扎夫根股份有限公司 | 2018-10-12 | — | — | CN | disclosed |