SCHEMBL25254512

SCHEMBL25254512

C[C@@H]1[C@H](O)CCN1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21813498 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL3321320 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL2183692 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL3275294 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL15719049 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL4775884 0.87 DPP4 (0.36)
SCHEMBL8926181 0.87 DPP4 (0.36)
SCHEMBL24016478 0.82 ATM (0.35) MAPT
SCHEMBL24016463 0.82 ATM (0.35) MAPT
SCHEMBL24016479 0.82 ATM (0.35) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024006881-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2024-01-04 WO disclosed
WO-2023133181-A1 KRAS INHIBITORS THERAS, INC. (US) 2023-07-13 WO disclosed
WO-2023130117-A1 DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF ENGRAIL THERAPEUTICS, INC. (US) 2023-07-06 WO disclosed