Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828523 | 0.79 | NPC1 (0.46) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL30589095 | 0.79 | NPC1 (0.46) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL30589030 | 0.79 | NPC1 (0.46) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL21828598 | 0.75 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL25384174 | 0.75 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL30209937 | 0.72 | TNKS (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL13046376 | 0.72 | TNKS (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL24322391 | 0.71 | CCKBR (0.46) | NOTUMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21828665 | 0.71 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL13046373 | 0.71 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856735-B1 | FUSED BICYCLIC HETEROCYCLES AS THERAPEUTIC AGENTS | UNIV NEW YORK (US) | 2023-09-06 | — | — | EP | disclosed |
| US-20210395222-A1 | Fused Bicyclic Heterocycles as Therapeutic Agents | NEW YORK UNIVERSITY | 2021-12-23 | — | — | US | disclosed |
| EP-3856735-A1 | FUSED BICYCLIC HETEROCYCLES AS THEREAPEUTIC AGENTS | New York University (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020073031-A1 | FUSED BICYCLIC HETEROCYCLES AS THEREAPEUTIC AGENTS | NEW YORK UNIVERSITY (US) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395222-A1 | Fused Bicyclic Heterocycles as Therapeutic Agents | NAMPT, NQO1, NAPRT | NOTUM 4430/4885MEN1 3379/4885KMT2A 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.