SCHEMBL21828686

SCHEMBL21828686

CC(O)C(N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACE P12821 10/20 0.61
MME P08473 9/20 0.61
CPA1 P15085 2/20 0.61
ACE2 Q9BYF1 2/20 0.61
FOLH1 Q04609 1/20 0.59
NAALAD2 Q9Y3Q0 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9822772 1.00 ACE (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL9822750 1.00 ACE (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL30123042 0.97 MME (0.58) ACEMMECPA1ACE2FOLH1
SCHEMBL29666764 0.95 ACE (0.56) ACEMMECPA1ACE2FOLH1
SCHEMBL30414144 0.94 MME (0.59) ACEMMECPA1ACE2FOLH1
SCHEMBL30417812 0.94 MME (0.59) ACEMMECPA1ACE2FOLH1
SCHEMBL30123357 0.94 ACE (0.55) ACEMMECPA1ACE2FOLH1
SCHEMBL29407166 0.93 ACE (0.54) ACEMMECPA1ACE2FOLH1
SCHEMBL30839478 0.92 ACE (0.53) ACEMMECPA1ACE2FOLH1
SCHEMBL31613781 0.91 NAALAD2 (0.62) ACEMMECPA1ACE2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020071258-A1 PROTEIN GLYCATION SUPPRESSANT 味の素株式会社 2020-04-09 WO disclosed