SCHEMBL29407166

SCHEMBL29407166

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nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACE P12821 8/20 0.54
MME P08473 6/20 0.54
CPA1 P15085 1/20 0.54
ACE2 Q9BYF1 1/20 0.54
ENPEP Q07075 3/20 0.53
FOLH1 Q04609 1/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.52
IL1RN P18510 1/20 0.49
ERAP2 Q6P179 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31195269 0.96 MME (0.50) ACEMMECPA1ACE2ENPEP
SCHEMBL30123042 0.93 MME (0.58) ACEMMECPA1ACE2ENPEP
SCHEMBL9822772 0.93 ACE (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL21828686 0.93 ACE (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL9822750 0.93 ACE (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL31500682 0.92 ENPEP (0.54) ACEMMECPA1ACE2ENPEP
SCHEMBL29968694 0.92 BACE1 (0.54) ACEMMEENPEP
SCHEMBL31613781 0.91 NAALAD2 (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL29370021 0.91 NAALAD2 (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL30400950 0.90 MME (0.53) ACEMMECPA1ACE2NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113528552-B Gene combination for synergetic catalysis of tea tree ester type catechin biosynthesis and application thereof 安徽农业大学 2024-01-09 CN disclosed
US-20220288028-A1 A THERAPEUTIC APPROACH FOR TREATING NON-INFECTIOUS OCULAR IMMUNOINFLAMMATORY DISORDERS THE SCHEPENS EYE RESEARCH INSTITUTE, INC. 2022-09-15 US disclosed
EP-3976594-A1 A THERAPEUTIC APPROACH FOR TREATING NON-INFECTIOUS OCULAR IMMUNOINFLAMMATORY DISORDERS The Schepens Eye Research Institute, Inc. (US) 2022-04-06 EP disclosed
CN-114206849-A Therapeutic methods for treating non-infectious ocular immunoinflammatory disorders 斯格本斯眼科研究所有限公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288028-A1 A THERAPEUTIC APPROACH FOR TREATING NON-INFECTIOUS OCULAR IMMUNOINFLAMMATORY DISORDERS MSR1, LTB4R2, LTB4R ACE 643/4885MME 685/4885CPA1 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.