Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714672 | 1.00 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL3821714 | 1.00 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL2281663 | 1.00 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL31556051 | 1.00 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL31093208 | 0.94 | TYMP (0.51) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL29799112 | 0.93 | KDM4E (0.52) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL3820892 | 0.92 | KDM4E (0.56) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL31342955 | 0.92 | TYMP (0.61) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL32677371 | 0.90 | TYMP (0.58) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL9017501 | 0.90 | TYMP (0.58) | TYMPKDM4EPOLA1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3861118-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2020072991-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |