SCHEMBL21830516

SCHEMBL21830516

Cc1ccc(C(C)c2ccc(O)cc2O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.71
TRPA1 O75762 1/20 0.50
LMNA P02545 1/20 0.50
CHRM1 P11229 1/20 0.50
SLC6A2 P23975 1/20 0.50
ADRA1A P35348 1/20 0.50
HTR2B P41595 1/20 0.50
ESR1 P03372 1/20 0.48
PDCD1 Q15116 1/20 0.48
ESR2 Q92731 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
ACHE P22303 1/20 0.43
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492458 1.00 TYR (0.71) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL28430447 0.90 TYR (0.79) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL28311703 0.85 TYR (0.66) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL10899030 0.85 TYR (0.51) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL369337 0.83 TYR (1.00) TYRESR1PDCD1ESR2CD274
SCHEMBL19806855 0.83 TYR (0.49) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL29394395 0.83 TYR (1.00) TYRESR1PDCD1ESR2CD274
SCHEMBL18815425 0.83 TYR (1.00) TYRESR1PDCD1ESR2CD274
SCHEMBL21830514 0.82 TYR (0.62) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL29492429 0.82 TYR (0.62) TYRTRPA1LMNACHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142680-B1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-10-18 EP disclosed
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-09-19 US disclosed
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-15 US disclosed
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-01 US disclosed
EP-4142680-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE Unilever IP Holdings B.V. (NL) 2023-03-08 EP disclosed
US-11260005-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2022-03-01 US disclosed
WO-2021219378-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B.V. (NL) 2021-11-04 WO disclosed
EP-3558246-B1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS UNILEVER IP HOLDINGS B V (NL) 2021-10-20 EP disclosed
US-20200108000-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2020-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11260005-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885TRPA1 2539/4885LMNA 4469/4885
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE NAA40, CRAT, NQO1 TYR 139/4885TRPA1 317/4885LMNA 3296/4885
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885TRPA1 2539/4885LMNA 4469/4885
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885TRPA1 2539/4885LMNA 4469/4885
US-20200108000-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885TRPA1 2539/4885LMNA 4469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.