SCHEMBL21830552

SCHEMBL21830552

CCCCCC(c1ccc(OC)cc1)c1ccc(O)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.53
BCHE P06276 1/20 0.53
ACHE P22303 1/20 0.53
MAPT P10636 3/20 0.44
MEN1 O00255 3/20 0.44
CYP3A4 P08684 3/20 0.44
KMT2A Q03164 3/20 0.44
PPARG P37231 1/20 0.44
F2 P00734 2/20 0.40
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
MMP1 P03956 2/20 0.39
MMP9 P14780 2/20 0.39
MMP13 P45452 2/20 0.39
ADAM17 P78536 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492387 1.00 TYR (0.53) TYRBCHEACHEMAPTMEN1
SCHEMBL21830474 0.91 TYR (0.57) TYRBCHEACHEMAPTMEN1
SCHEMBL29492431 0.91 TYR (0.57) TYRBCHEACHEMAPTMEN1
SCHEMBL21830548 0.86 TYR (0.69) TYRBCHEACHEMAPTMEN1
SCHEMBL29492260 0.86 TYR (0.69) TYRBCHEACHEMAPTMEN1
SCHEMBL21830529 0.85 TYR (0.42) TYRBCHEACHEMAPTMEN1
SCHEMBL4660955 0.85 TYR (0.53) TYRBCHEACHEMAPTMEN1
SCHEMBL29492313 0.85 TYR (0.42) TYRBCHEACHEMAPTMEN1
SCHEMBL21830489 0.85 TYR (0.55) TYRMAPTMEN1CYP3A4KMT2A
SCHEMBL29492449 0.85 TYR (0.55) TYRMAPTMEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142680-B1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-10-18 EP disclosed
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-09-19 US disclosed
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-15 US disclosed
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-01 US disclosed
EP-4142680-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE Unilever IP Holdings B.V. (NL) 2023-03-08 EP disclosed
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-03-07 US disclosed
CN-115484921-A N, N' -diacetylcystine in-stable cosmetic compositions 联合利华知识产权控股有限公司 2022-12-16 CN disclosed
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2022-07-07 US disclosed
CN-110121330-B Personal care compositions with glutathione precursors comprising 4-substituted resorcinols and amino acids 联合利华知识产权控股有限公司 2022-04-29 CN disclosed
US-11260005-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2022-03-01 US disclosed
WO-2021219378-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B.V. (NL) 2021-11-04 WO disclosed
EP-3558246-B1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS UNILEVER IP HOLDINGS B V (NL) 2021-10-20 EP disclosed
US-20200108000-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2020-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885BCHE 3893/4885ACHE 2876/4885
US-11260005-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885BCHE 3893/4885ACHE 2876/4885
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885BCHE 3893/4885ACHE 2876/4885
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE NAA40, CRAT, NQO1 TYR 139/4885BCHE 1225/4885ACHE 1038/4885
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885BCHE 3893/4885ACHE 2876/4885
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885BCHE 3893/4885ACHE 2876/4885
US-20200108000-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885BCHE 3893/4885ACHE 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.