SCHEMBL2183139

SCHEMBL2183139

CCCCCCCC/C=C\CCCCCCCCNNC(N)=O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.58
SOAT1 P35610 2/20 0.58
MEN1 O00255 1/20 0.58
TP53 P04637 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C19 P33261 1/20 0.58
KMT2A Q03164 1/20 0.58
KDM4E B2RXH2 2/20 0.53
PPARA Q07869 1/20 0.51
SLC6A5 Q9Y345 2/20 0.51
EPHX2 P34913 7/20 0.50
CNR1 P21554 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2183144 1.00 FAAH (0.58) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL28059419 0.89 EPHX1 (0.50)
SCHEMBL29047889 0.89 EPHX1 (0.50)
SCHEMBL8741361 0.89 EPHX1 (0.50)
SCHEMBL8587015 0.89 EPHX1 (0.50)
SCHEMBL11032495 0.89 EPHX1 (0.50)
SCHEMBL9029626 0.89 EPHX1 (0.50)
SCHEMBL28891444 0.89 EPHX1 (0.50)
SCHEMBL253169 0.87 HDAC1 (0.47)
SCHEMBL29224695 0.83 FAAH (0.49) FAAHSOAT1MEN1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10087389-B2 Lubricating oil composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2018-10-02 US disclosed
US-20170198234-A1 LUBRICATING OIL COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2017-07-13 US disclosed
US-20160340603-A1 LUBRICATING OIL COMPOSITION FOR DIFFERENTIAL GEAR UNIT JTEKT CORPORATION (JP) 2016-11-24 US disclosed
EP-1686167-B1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2016-05-25 EP disclosed
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
US-20080248981-A1 Lubricating base oil, an ashless friction modifier and a phosphorus-containing anti-wear agent; increasing the isomerization rate from normal paraffins to isoparaffins, improving the low temperature viscosity property by lowering the viscosity of the lubricating base oil NIPPON OIL CORPORATION 2008-10-09 US disclosed
US-20080234153-A1 LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2008-09-25 US disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed