Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16346465 | 0.88 | PTGS2 (0.34) | KCNH2DDR1NPC1RAB9A | |
| SCHEMBL17732142 | 0.88 | DDR1 (0.33) | KCNH2DDR1NPC1RAB9A | |
| SCHEMBL17732195 | 0.88 | DDR1 (0.35) | KCNH2DDR1NPC1RAB9AEGLN1 | |
| SCHEMBL20233511 | 0.88 | KCNH2 (0.36) | KCNH2NPC1RAB9A | |
| SCHEMBL21750098 | 0.87 | EGLN1 (0.38) | KCNH2DDR1EGLN1 | |
| SCHEMBL21761678 | 0.87 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL21750127 | 0.86 | DDR1 (0.35) | KCNH2DDR1EGLN1 | |
| SCHEMBL21750110 | 0.86 | DDR1 (0.33) | KCNH2DDR1EGLN1 | |
| SCHEMBL21832208 | 0.86 | — | — | |
| SCHEMBL21832210 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612301-B | Imidazopyrimidine derivatives having sulfur-containing phenyl and pyridyl substituents | 先正达参股股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-3621965-B1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-23 | — | — | EP | disclosed |
| US-10945435-B2 | Imidazopyrimidine derivatives with sulfur containing phenyl and pyridyl substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-10945435-B2 | Imidazopyrimidine derivatives with sulfur containing phenyl and pyridyl substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-20200100502-A1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-02 | — | — | US | disclosed |
| US-20200100502-A1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10945435-B2 | Imidazopyrimidine derivatives with sulfur containing phenyl and pyridyl substituents | PNPO, DDT, TH | KCNH2 3019/4885DDR1 3397/4885NPC1 3836/4885 |
| US-20200100502-A1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | PNPO, DDT, TH | KCNH2 3019/4885DDR1 3397/4885NPC1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.