Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183218 | 1.00 | RECQL (0.60) | RECQLHPGDALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL20456508 | 0.81 | MEN1 (0.81) | RECQLHPGDALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL20456509 | 0.81 | MEN1 (0.81) | RECQLHPGDALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL6097513 | 0.79 | MAPT (0.58) | RECQLHPGDALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL6095640 | 0.77 | MEN1 (0.65) | RECQLHPGDALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL19508692 | 0.76 | CTSL (0.73) | RECQLMEN1KMT2ACYP1A2PDE4D | |
| SCHEMBL4176326 | 0.76 | RECQL (0.68) | RECQLHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4176324 | 0.76 | RECQL (0.68) | RECQLHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4188471 | 0.74 | KDM4E (0.73) | RECQLHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4188465 | 0.74 | KDM4E (0.73) | RECQLHPGDALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | RECQL 1939/4885HPGD 188/4885ALDH1A1 458/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | RECQL 1939/4885HPGD 188/4885ALDH1A1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.