Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444692 | 1.00 | CDK1 (0.33) | CDK1CDK2KDRABL1 | |
| SCHEMBL21832221 | 0.90 | PTGS1 (0.31) | — | |
| SCHEMBL29386369 | 0.90 | PTGS1 (0.31) | — | |
| SCHEMBL21832207 | 0.88 | KCNH2 (0.30) | — | |
| SCHEMBL21832215 | 0.88 | — | — | |
| SCHEMBL21832226 | 0.87 | PTGS2 (0.33) | — | |
| SCHEMBL21832232 | 0.86 | — | — | |
| SCHEMBL21832222 | 0.85 | UGCG (0.31) | — | |
| SCHEMBL24261719 | 0.83 | — | — | |
| SCHEMBL21832212 | 0.83 | KCNH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621965-B1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-23 | — | — | EP | disclosed |
| US-10945435-B2 | Imidazopyrimidine derivatives with sulfur containing phenyl and pyridyl substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-20200100502-A1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10945435-B2 | Imidazopyrimidine derivatives with sulfur containing phenyl and pyridyl substituents | PNPO, DDT, TH | CDK1 245/4885CDK2 190/4885KDR 1769/4885 |
| US-20200100502-A1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | PNPO, DDT, TH | CDK1 245/4885CDK2 190/4885KDR 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.