SCHEMBL21834233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21834295	0.91	CTSA (0.37)	CTSAMAOBKCNH2CACNA1BCYP2D6
	SCHEMBL21834242	0.84	MAOB (0.39)	CTSAMAOBKCNH2CACNA1BLMNA
	SCHEMBL23243896	0.83	CTSA (0.40)	CTSAMAOBKCNH2CACNA1BKDM4E
	SCHEMBL21834303	0.81	MAOB (0.37)	MAOBKCNH2CACNA1BKDM4EALDH1A1
	SCHEMBL21834297	0.78	MAOB (0.39)	CTSAMAOBKCNH2CACNA1BLMNA
	SCHEMBL23589505	0.77	CTSA (0.40)	CTSAMAOBKCNH2CACNA1B
	SCHEMBL29229816	0.76	KDM4E (0.36)	CTSAMAOBKCNH2CACNA1BKDM4E
	SCHEMBL23678491	0.75	KCNH2 (0.38)	MAOBKCNH2CACNA1BKDM4EALDH1A1
	SCHEMBL23678346	0.74	KCNH2 (0.39)	MAOBKCNH2CACNA1BKDM4EALDH1A1
	SCHEMBL21834330	0.74	MAOB (0.40)	CTSAMAOBKCNH2CACNA1BCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.