SCHEMBL21834236

SCHEMBL21834236

Cc1nnc(CC(OC(N)=O)c2cccc(-c3ccc(Cl)cc3C(F)(F)F)c2)o1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SCN9A Q15858 2/20 0.45
▸ CTSA P10619 15/20 0.43
▸ AKR1C3 P42330 2/20 0.37
▸ AKR1C2 P52895 2/20 0.37
▸ AKR1B10 O60218 1/20 0.36
▸ AKR1C4 P17516 1/20 0.36
▸ AKR1C1 Q04828 1/20 0.36
▸ ELANE P08246 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21834285 0.91 CYP2C9 (0.44) SCN9ACTSAAKR1C3AKR1C2ELANE
SCHEMBL21834248 0.86 CTSA (0.52) CTSA
SCHEMBL21834307 0.85 CTSA (0.43) CTSAELANE
SCHEMBL21834313 0.84 CTSA (0.44) CTSAELANE
SCHEMBL21834293 0.84 CTSA (0.42) SCN9ACTSAAKR1C3AKR1C2AKR1B10
SCHEMBL21834283 0.83 CTSA (0.48) SCN9ACTSA
SCHEMBL21834335 0.83 CTSA (0.43) CTSAELANE
SCHEMBL23243881 0.82 CTSA (0.44) SCN9ACTSAAKR1C3AKR1C2AKR1B10
SCHEMBL21834245 0.80 CTSA (0.41) CTSAELANE
SCHEMBL21834276 0.79 CTSA (0.44) CTSAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO claimed
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US disclosed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-03-14 — — US disclosed
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. 2022-01-27 — — US disclosed
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. 2022-01-27 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 SCN9A 556/4885CTSA 3755/4885AKR1C3 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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