SCHEMBL21834418

SCHEMBL21834418

CCOC(=O)C(C)=CC(F)(C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.39
NPSR1 Q6W5P4 4/20 0.35
ALDH1A1 P00352 5/20 0.34
LMNA P02545 4/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 5/20 0.33
KMT2A Q03164 4/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 2/20 0.33
MEN1 O00255 3/20 0.32
MAPK1 P28482 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR1 P21453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPA1 O75762 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22729907 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL22729905 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL25348177 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL25348953 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL21381274 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL25348897 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL22729906 0.93 GLO1 (0.37) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL27948861 0.87 GLO1 (0.35) GLO1NPSR1ALDH1A1LMNAHSD17B10
SCHEMBL25347323 0.87 HCAR2 (0.33) TSHR
SCHEMBL21409819 0.86 GLO1 (0.34) GLO1NPSR1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023153586-A1 NOVEL META-POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (META-POSS) COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION COMPRISING META-POSS COMPOUND PRODUCED THEREBY 주식회사 파이오셀 2023-08-17 WO claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
WO-2023153586-A1 NOVEL META-POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (META-POSS) COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION COMPRISING META-POSS COMPOUND PRODUCED THEREBY 주식회사 파이오셀 2023-08-17 WO disclosed
CN-108713031-B Random copolymer, resist composition, color filter, and method for producing random copolymer DIC株式会社 2020-10-02 CN disclosed
WO-2020066657-A1 POLYMER, LIQUID-CRYSTAL COMPOSITION, RETARDATION LAYER, OPTICAL FILM, POLARIZER, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-04-02 WO disclosed
CN-107141375-B Norborneol alkenes ternary polymerization catalyst, preparation method and method for ternary polymerization 宁波工程学院 2019-06-11 CN disclosed
CN-108425104-A A kind of coating production using sulfhydryl compound as transition zone 江苏菲沃泰纳米科技有限公司 2018-08-21 CN disclosed
CN-107141375-A Norborneol alkenes ternary polymerization catalyst, preparation method and method for ternary polymerization 宁波工程学院 2017-09-08 CN disclosed