Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 7/20 | 0.36 |
| ▸ | CDK8 | P49336 | 7/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698817 | 0.95 | CHRM1 (0.47) | CHRM1CCNCCDK8GRM2 | |
| SCHEMBL23698808 | 0.89 | CHRM1 (0.40) | CHRM1CCNCCDK8GRM2MET | |
| SCHEMBL23698833 | 0.85 | CHRM1 (0.47) | CHRM1CCNCCDK8GRM2 | |
| SCHEMBL23698798 | 0.85 | CHRM1 (0.49) | CHRM1GRM2MET | |
| SCHEMBL23713433 | 0.84 | CHRM1 (0.46) | CHRM1CCNCCDK8GRM2 | |
| SCHEMBL23698891 | 0.81 | BRD4 (0.36) | CHRM1 | |
| SCHEMBL21834470 | 0.81 | KAT6A (0.35) | CHRM1 | |
| SCHEMBL23698803 | 0.78 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL21873385 | 0.77 | CHRM1 (0.45) | CHRM1CCNCCDK8GRM2MET | |
| SCHEMBL30428285 | 0.77 | CHRM1 (0.45) | CHRM1CCNCCDK8GRM2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020067457-A1 | CONDENSED-CYCLIC COMPOUND | 武田薬品工業株式会社 | 2020-04-02 | — | — | WO | disclosed |