Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347353 | 0.89 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL31369148 | 0.81 | KMT2A (0.75) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| SCHEMBL87791 | 0.81 | KMT2A (0.75) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| SCHEMBL13475582 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| Charcoal, Activated SCHEMBL8358164 | 0.79 | KMT2A (0.72) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| Water SCHEMBL6228901 | 0.79 | KMT2A (0.72) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| SCHEMBL31369119 | 0.79 | KMT2A (0.72) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| Hydrochloric Acid SCHEMBL27723543 | 0.79 | KMT2A (0.72) | KDM4EALDH1A1KMT2ASMN1; SMN2CES2 | |
| SCHEMBL10435349 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL6115219 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1ALOX15KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437159-A | Cyclic carbonate nucleoside compound and application thereof | 佛山市晨康生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3856178-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |