Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708237 | 0.90 | POLB (0.52) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708314 | 0.84 | POLB (0.55) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708288 | 0.82 | POLB (0.51) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708227 | 0.81 | KEAP1 (0.55) | MAPTKEAP1NFE2L2BMP1 | |
| SCHEMBL21708217 | 0.81 | POLB (0.47) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708308 | 0.81 | POLB (0.51) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708215 | 0.80 | POLB (0.53) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708291 | 0.79 | POLB (0.48) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL10805165 | 0.78 | POLB (0.68) | POLBMCOLN3MAPTKMT2AMEN1 | |
| SCHEMBL21708313 | 0.77 | KEAP1 (0.48) | POLBKMT2AMEN1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020067398-A1 | BIARYL SULFONAMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST CELL INVASION OF FILOVIRUS | 国立大学法人北海道大学 | 2020-04-02 | — | — | WO | disclosed |