Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11514556 | 0.91 | MAPK1 (0.56) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Benzoic Acid SCHEMBL28643205 | 0.87 | MAPK1 (0.73) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL6053597 | 0.85 | MAPK1 (0.65) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL6053888 | 0.85 | MAPK1 (0.65) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Benzoic Acid SCHEMBL6053600 | 0.83 | TSHR (0.61) | MAPK1TDP1ALDH1A1KMT2AMAPT | |
| Benzoic Acid SCHEMBL6053894 | 0.83 | TSHR (0.61) | MAPK1TDP1ALDH1A1KMT2AMAPT | |
| Benzoic Acid SCHEMBL2020364 | 0.83 | TSHR (0.61) | MAPK1TDP1ALDH1A1KMT2AMAPT | |
| SCHEMBL27620 | 0.83 | MAPK1 (1.00) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Benzoic Acid SCHEMBL2239809 | 0.82 | MAPK1 (0.65) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL4576866 | 0.82 | MAPK1 (0.81) | MAPK1HIF1ATDP1SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860318-A1 | HOT MELT COATING AGENT FOR COMPONENT-MOUNTED ELECTRONIC CIRCUIT BOARD | Sekisui Fuller Company, Ltd. (JP) | 2021-08-04 | — | — | EP | claimed |
| US-20210222027-A1 | HOT MELT COATING AGENT FOR COMPONENT-MOUNTED ELECTRONIC CIRCUIT BOARD | SEKISUI FULLER COMPANY, LTD. (JP) | 2021-07-22 | — | — | US | claimed |
| CN-112772005-A | Hot melt coating agent for electronic circuit mounting substrate | 积水富乐株式会社 | 2021-05-07 | — | — | CN | claimed |
| WO-2020066882-A1 | HOT MELT COATING AGENT FOR COMPONENT-MOUNTED ELECTRONIC CIRCUIT BOARD | 積水フーラー株式会社 | 2020-04-02 | — | — | WO | claimed |
| EP-3860318-A1 | HOT MELT COATING AGENT FOR COMPONENT-MOUNTED ELECTRONIC CIRCUIT BOARD | Sekisui Fuller Company, Ltd. (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-20210222027-A1 | HOT MELT COATING AGENT FOR COMPONENT-MOUNTED ELECTRONIC CIRCUIT BOARD | SEKISUI FULLER COMPANY, LTD. (JP) | 2021-07-22 | — | — | US | disclosed |
| CN-112772005-A | Hot melt coating agent for electronic circuit mounting substrate | 积水富乐株式会社 | 2021-05-07 | — | — | CN | disclosed |
| WO-2020066882-A1 | HOT MELT COATING AGENT FOR COMPONENT-MOUNTED ELECTRONIC CIRCUIT BOARD | 積水フーラー株式会社 | 2020-04-02 | — | — | WO | disclosed |