Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444012 | 0.94 | MAPK1 (0.71) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL3453675 | 0.93 | MAPK1 (0.53) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Terephthalic Acid SCHEMBL2442144 | 0.93 | MAPK1 (0.53) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Ethylene Glycol SCHEMBL226247 | 0.89 | MAPK1 (0.65) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Ethylene Glycol SCHEMBL28877079 | 0.88 | MAPT (0.49) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL9988314 | 0.86 | MAPK1 (0.51) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL3669896 | 0.85 | MAPK1 (0.55) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL204567 | 0.83 | MAPK1 (0.71) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| SCHEMBL2020359 | 0.83 | MAPK1 (0.71) | MAPK1HIF1ATDP1SLC6A3HTR1A | |
| Benzoic Acid SCHEMBL21834840 | 0.82 | MAPK1 (0.70) | MAPK1HIF1ATDP1SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137146-A9 | CELLULOSE ESTER COMPOSITION AND PROCESS FOR PRODUCING ARTICLES THEREFROM | CELANESE INTERNATIONAL CORPORATION (US) | 2024-05-23 | — | — | WO | claimed |
| US-20240026130-A1 | Bio-Based Polymer Composition Containing Odor Masking Agent | CELANESE INT CORP (US) | 2024-01-25 | — | — | US | claimed |
| WO-2024020195-A1 | COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT | CELANESE INTERNATIONAL CORPORATION (US) | 2024-01-25 | — | — | WO | claimed |
| WO-2024020193-A1 | BIO-BASED POLYMER COMPOSITION CONTAINING ODOR MASKING AGENT | CELANESE INTERNATIONAL CORPORATION (US) | 2024-01-25 | — | — | WO | claimed |
| US-20240026122-A1 | Composition Containing Cellulose Ester Polymer With Enhanced Melt Strength Agent | CELANESE INTERNATIONAL CORPORATION | 2024-01-25 | — | — | US | claimed |
| WO-2023244729-A1 | CELLULOSE ESTER POLYMER PRODUCT WITH INCREASED MELT FLOW PROPERTIES AND REFLECTANCE | CELANESE INTERNATIONAL CORPORATION (US) | 2023-12-21 | — | — | WO | claimed |
| EP-4258858-A1 | FOAM FORMED FROM CELLULOSE ESTER COMPOSITION | Celanese International Corporation (US) | 2023-10-18 | — | — | EP | claimed |
| CN-116867362-A | Foams formed from cellulose ester compositions | 国际人造丝公司 | 2023-10-10 | — | — | CN | claimed |
| EP-4247606-A1 | CELLULOSE ESTER COMPOSITION AND ARTICLES MADE THEREFROM | Celanese International Corporation (US) | 2023-09-27 | — | — | EP | claimed |
| WO-2023172722-A1 | CELLULOSE ESTER POLYMER COMPOSITION AND MOLDED ARTICLES MADE THEREFROM | CELANESE INTERNATIONAL CORPORATION (US) | 2023-09-14 | — | — | WO | claimed |
| US-20230226735-A1 | Process and System For Blending A Plasticizer With A Polysaccharide Ester Polymer | CELANESE INTERNATIONAL CORPORATION | 2023-07-20 | — | — | US | claimed |
| US-20230226734-A1 | Cellulose Ester Composition and Process For Producing Articles Therefrom | CELANESE INT CORP (US) | 2023-07-20 | — | — | US | claimed |
| WO-2023137146-A1 | CELLULOSE ESTER COMPOSITION AND PROCESS FOR PRODUCING ARTICLES THEREFROM | CELANESE INTERNATIONAL CORPORATION (US) | 2023-07-20 | — | — | WO | claimed |
| WO-2023096882-A1 | BIODEGRADABLE COMPOSITE ARTICLE | CELANESE INTERNATIONAL CORPORATION (US) | 2023-06-01 | — | — | WO | claimed |
| WO-2022125916-A1 | FOAM FORMED FROM CELLULOSE ESTER COMPOSITION | CELANESE INTERNATIONAL CORPORATION (US) | 2022-06-16 | — | — | WO | claimed |
| US-20220185978-A1 | Foam Formed From Cellulose Ester Composition | CELANESE INT CORP (US) | 2022-06-16 | — | — | US | claimed |
| WO-2022109228-A1 | CELLULOSE ESTER COMPOSITION AND ARTICLES MADE THEREFROM | CELANESE INTERNATIONAL CORPORATION (US) | 2022-05-27 | — | — | WO | claimed |
| US-4368285-A | MOLDING MATERIALS | DART INDUSTRIES INC. (US) | 1983-01-11 | — | — | US | claimed |
| US-4340526-A | ESTER PLASTICIZERS TO LOWER THE MELT VISCOSITY | EASTMAN KODAK COMPANY (US) | 1982-07-20 | — | — | US | claimed |
| US-4172824-A | PLASTICIZER | EASTMAN KODAK COMPANY (US) | 1979-10-30 | — | — | US | claimed |