SCHEMBL21834874

SCHEMBL21834874

CCN(CC(O)c1cccc(O)c1)C(=O)OCCl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
HIF1A Q16665 4/20 0.44
LMNA P02545 3/20 0.44
GALR3 O60755 1/20 0.44
ADRB1 P08588 2/20 0.43
ADRA1A P35348 2/20 0.43
ADRB2 P07550 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRB3 P13945 1/20 0.43
TSHR P16473 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
NFKB1 P19838 1/20 0.43
DRD1 P21728 1/20 0.43
HTR7 P34969 1/20 0.43
ADRA1B P35368 1/20 0.43
DRD3 P35462 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21860498 0.82 MEN1 (0.50) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL21860505 0.82 MEN1 (0.52) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL21834849 0.81 MEN1 (0.61) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL10551323 0.76 ALOX5 (0.56) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL9722083 0.76 ALOX5 (0.56) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL21860501 0.76 MEN1 (0.46) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL21860503 0.75 MEN1 (0.43) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL24951572 0.73 SLC22A1 (0.59) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL6491746 0.73 SLC22A1 (0.59) MEN1KMT2AHIF1ALMNAGALR3
SCHEMBL8439197 0.73 SLC22A1 (0.59) MEN1KMT2AHIF1ALMNAGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220040318-A1 PRIMARY AMINE COMPOUND OR SECONDARY AMINE COMPOUND-ACIDIC POLYSACCHARIDE CONJUGATE AND PRODUCTION METHOD THEREFOR SEIKAGAKU CORPORATION (JP) 2022-02-10 US disclosed
WO-2020067507-A1 PRIMARY AMINE COMPOUND- OR SECONDARY AMINE COMPOUND-ACIDIC POLYSACCHARIDE CONJUGATE, AND METHOD FOR PRODUCING SAME 生化学工業株式会社 2020-04-02 WO disclosed
WO-2020067507-A1 PRIMARY AMINE COMPOUND- OR SECONDARY AMINE COMPOUND-ACIDIC POLYSACCHARIDE CONJUGATE, AND METHOD FOR PRODUCING SAME 生化学工業株式会社 2020-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220040318-A1 PRIMARY AMINE COMPOUND OR SECONDARY AMINE COMPOUND-ACIDIC POLYSACCHARIDE CONJUGATE AND PRODUCTION METHOD THEREFOR ALG1, NGLY1, SAT1 MEN1 91/4885KMT2A 318/4885HIF1A 1849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.