Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.58 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21835708 | 0.89 | CYP1A2 (0.47) | CYP1A2ALOX5APFEN1CHRM5CBFB | |
| SCHEMBL21835679 | 0.88 | CYP1A2 (0.44) | CYP1A2ALOX5APFEN1CHRM5P2RY1 | |
| SCHEMBL21835681 | 0.84 | CYP1A2 (0.42) | CYP1A2ALOX5APFEN1CHRM5P2RY1 | |
| SCHEMBL21835668 | 0.82 | CYP1A2 (0.55) | CYP1A2ALOX5APFEN1CBFBGPR3 | |
| SCHEMBL21835698 | 0.81 | CYP1A2 (0.54) | CYP1A2ALOX5APFEN1CHRM5P2RY1 | |
| SCHEMBL21835707 | 0.77 | ALOX5AP (0.44) | CYP1A2ALOX5APFEN1CHRM5CBFB | |
| SCHEMBL21835654 | 0.77 | CYP1A2 (0.49) | CYP1A2ALOX5APFEN1CBFB | |
| SCHEMBL31733962 | 0.77 | CYP1A2 (0.49) | CYP1A2ALOX5APFEN1CBFB | |
| SCHEMBL20190641 | 0.75 | CYP1A2 (0.66) | CYP1A2ALOX5APFEN1CBFBDYRK1A | |
| SCHEMBL20209012 | 0.75 | CYP1A2 (0.74) | CYP1A2ALOX5APFEN1CBFBDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479844-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-20210403476-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2021-12-30 | — | — | US | disclosed |
| US-20210403476-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2021-12-30 | — | — | US | disclosed |
| EP-3856193-A1 | ION CHANNEL MODULATORS | Praxis Precision Medicines, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020069322-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403476-A1 | ION CHANNEL MODULATORS | SCN1A, SCN3A, SCN2A | CYP1A2 2873/4885ALOX5AP 1210/4885FEN1 4819/4885 |
| US-12479844-B2 | Ion channel modulators | SCN1A, SCN3A, SCN2A | CYP1A2 2873/4885ALOX5AP 1210/4885FEN1 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.