Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 3/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21835679 | 0.83 | CYP1A2 (0.44) | CYP1A2ALOX5APFEN1FFAR4GPR3 | |
| SCHEMBL21835746 | 0.82 | CYP1A2 (0.41) | CYP1A2ALOX5APFEN1FFAR4P2RY1 | |
| SCHEMBL21835686 | 0.81 | CYP1A2 (0.58) | CYP1A2ALOX5APFEN1FFAR4GPR3 | |
| SCHEMBL31733961 | 0.80 | CYP1A2 (0.51) | CYP1A2ALOX5APFEN1FFAR4SCN5A | |
| SCHEMBL21835703 | 0.80 | CYP1A2 (0.51) | CYP1A2ALOX5APFEN1FFAR4SCN5A | |
| SCHEMBL21835707 | 0.80 | ALOX5AP (0.44) | CYP1A2ALOX5APFEN1GPR3P2RY1 | |
| SCHEMBL21835708 | 0.80 | CYP1A2 (0.47) | CYP1A2ALOX5APFEN1FFAR4SCN5A | |
| SCHEMBL21835701 | 0.79 | ALOX5AP (0.44) | CYP1A2ALOX5APFEN1FFAR4GPR3 | |
| SCHEMBL20203802 | 0.76 | CYP1A2 (0.48) | CYP1A2ALOX5APFEN1SCN5AKCNH2 | |
| SCHEMBL21835644 | 0.75 | CYP1A2 (0.32) | CYP1A2ALOX5APFEN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479844-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-20210403476-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2021-12-30 | — | — | US | disclosed |
| US-20210403476-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2021-12-30 | — | — | US | disclosed |
| CN-113573713-A | Ion channel modulators | 普拉克西斯精密药物股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| EP-3856193-A1 | ION CHANNEL MODULATORS | Praxis Precision Medicines, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020069322-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403476-A1 | ION CHANNEL MODULATORS | SCN1A, SCN3A, SCN2A | CYP1A2 2873/4885ALOX5AP 1210/4885FEN1 4819/4885 |
| US-12479844-B2 | Ion channel modulators | SCN1A, SCN3A, SCN2A | CYP1A2 2873/4885ALOX5AP 1210/4885FEN1 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.