Nimorazole

Nimorazole

SCHEMBL21836

O=[N+]([O-])c1cncn1CCN1CCOCC1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
POLB P06746 3/20 0.45
MEN1 O00255 2/20 0.45
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 2/20 0.41
KCNJ1 P48048 1/20 0.41
PKM P14618 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CTSB P07858 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nimorazole SCHEMBL2555788 0.99 POLB (0.44) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2556141 0.93 PKM (0.43) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2552669 0.93 MEN1 (0.40) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2555578 0.91 PKM (0.44) KMT2APOLBMEN1ALDH1A1MAPT
Nimorazole SCHEMBL2549842 0.91 GLA (0.46) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2555550 0.90 KMT2A (0.38) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2558233 0.90 KMT2A (0.38) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2555549 0.90 KMT2A (0.38) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL15570120 0.89 MEN1 (0.38) KMT2APOLBMEN1ALDH1A1SMN1; SMN2
Nimorazole SCHEMBL2552501 0.89 GLA (0.43) KMT2APOLBMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7213 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-12570704-B2 Functionally modified maytansinoids and compositions and methods of use thereof University of Georgie Research Foundation, Inc. (US) 2026-03-10 US claimed
US-12544444-B2 Administration of tailored feedstock to increase antibiotic susceptibility THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2026-02-10 US claimed
EP-4680248-A1 PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM Topelia Aust Limited (ACN 652 771 670) (AU) 2026-01-21 EP claimed
EP-4308181-B1 SUTURES UNIV BELFAST (GB) 2025-11-19 EP claimed
US-12458694-B2 Methods for treatment of accelerated atherosclerosis and rheumatoid arthritis with an anti-Apo B100 antibody ABCENTRA, LLC (US) 2025-11-04 US claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
US-20250268934-A1 Compositions and Methods for the Treatment of Bacterial Vaginosis WAYNE STATE UNIVERSITY (US) 2025-08-28 US claimed
EP-4602049-A1 SOS1 INHIBITORS Bayer Aktiengesellschaft (DE) 2025-08-20 EP claimed
EP-4587439-A1 SULFONE-SUBSTITUTED PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER Bayer Aktiengesellschaft (DE) 2025-07-23 EP claimed
WO-1995032720-A1 COMPOSITION FOR TREATING GASTROINTESTINAL DISORDERS HYBRID SCIENTIFIC PTY. LTD. (AU) 1995-12-07 WO claimed
EP-0595890-A1 ANTIMICROBIAL TREATMENT METHODS AND COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 EP claimed
US-5256684-A Administering bismuth compound and antimicrobial agent THE PROCTER & GAMBLE COMPANY (US) 1993-10-26 US claimed
EP-0543811-A1 TOPICAL TREATMENT OF BLEPHARITIS Bloom, Leonard (US) 1993-06-02 EP claimed
WO-1993001818-A1 ANTIMICROBIAL TREATMENT METHODS AND COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-02-04 WO claimed
EP-0206625-B1 COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS Marshall, Barry James, Dr. (US) 1992-09-30 EP claimed
WO-1992003133-A1 TOPICAL TREATMENT OF BLEPHARITIS BLOOM, LEONARD (US) 1992-03-05 WO claimed
EP-0462631-A1 Methods and compositions for the treatment of gastrointestinal disorders Marshall, Barry James, Dr. (US) 1991-12-27 EP claimed
US-4957918-A Topical treatment of blepharitis Bloom, Leonard (US) 1990-09-18 US claimed
US-4218449-A NITROIMIDAZOLE COMPOUNDS Simoons, John R. A. (US) 1980-08-19 US claimed