Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 9/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239786 | 0.85 | MEN1 (0.65) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL17354700 | 0.79 | MEN1 (0.68) | KCNK3KCNK9KMT2AMEN1POLB | |
| SCHEMBL15177176 | 0.78 | KCNK3 (1.00) | KCNK3KCNK9KMT2AMEN1POLB | |
| SCHEMBL18327156 | 0.78 | MAPT (0.79) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL20898931 | 0.78 | KMT2A (0.61) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL7240676 | 0.77 | MAPT (0.59) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL23587927 | 0.75 | MAPT (0.62) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL4258402 | 0.75 | KCNK3 (0.64) | KCNK3KCNK9KMT2AMEN1POLB | |
| SCHEMBL4253897 | 0.75 | KCNK3 (0.93) | KCNK3KCNK9KMT2AMEN1POLB | |
| SCHEMBL7238805 | 0.74 | RAB9A (0.78) | KMT2AMEN1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | KCNK3 4184/4885KCNK9 4523/4885KMT2A 400/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | KCNK3 4184/4885KCNK9 4523/4885KMT2A 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.