Dimethylamine

Dimethylamine

SCHEMBL21836445

CNC.Cc1cccc(C)n1

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.60
CCR8 P51685 1/20 0.60
NOS3 P29474 1/20 0.55
NOS2 P35228 1/20 0.55
RAB9A P51151 5/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
P2RX7 Q99572 1/20 0.45
GRM5 P41594 5/20 0.42
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 3/20 0.41
NPC1 O15118 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HDAC6 Q9UBN7 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
PKM P14618 2/20 0.41
CYP2C19 P33261 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9611 0.90
SCHEMBL30421349 0.90
SCHEMBL1771685 0.90 CCR1 (0.71) CCR1CCR8NOS3NOS2RAB9A
SCHEMBL184761 0.87
Bromide SCHEMBL5437785 0.87
Iodide SCHEMBL8148528 0.87
Fluoride SCHEMBL38652089 0.87
Hydrogen Sulfide SCHEMBL20214420 0.87
SCHEMBL17822110 0.87
Ammonia Solution, Strong SCHEMBL18983640 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4406609-A2 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND Day One Biopharmaceuticals, Inc. (US) 2024-07-31 EP disclosed
EP-3632441-A2 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND Millennium Pharmaceuticals, Inc. (US) 2020-04-08 EP disclosed