⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537867 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL9775477 | 0.95 | — | — | |
| SCHEMBL27530719 | 0.95 | — | — | |
| SCHEMBL27937152 | 0.78 | — | — | |
| SCHEMBL15291400 | 0.67 | — | — | |
| SCHEMBL4595933 | 0.63 | ALDH1A1 (0.31) | — | |
| Nitrous Acid SCHEMBL5809368 | 0.63 | — | — | |
| SCHEMBL1665889 | 0.59 | — | — | |
| SCHEMBL10788545 | 0.59 | — | — | |
| SCHEMBL15133749 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837479-B | Hydrazine nitrile cathepsin K inhibitor and its application in treatment osteoarthritis drugs are prepared | 吉林大学 | 2017-10-27 | — | — | CN | claimed |
| CN-104269568-B | A kind of passive temperature-sensitive sensing element | 青岛中阳消防科技有限公司 | 2017-08-25 | — | — | CN | claimed |
| US-20170172970-A1 | VECTOR DELIVERY-BASED MICROBICIDES | RUSH UNIVERSITY MEDICAL CENTER (US) | 2017-06-22 | — | — | US | claimed |
| EP-2978794-B1 | CURABLE MIXTURES BASED ON XYLYLENE BISMALEIMIDE | EVONIK DEGUSSA GMBH (DE) | 2017-05-03 | — | — | EP | claimed |
| US-9603841-B2 | Vector delivery-based microbicides | RUSH UNIVERSITY MEDICAL CENTER (US) | 2017-03-28 | — | — | US | claimed |
| CN-104987301-B | Nitrile cathepsin K inhibitors using trifluoroethylamino groups as P2-P3 linkers, and application of inhibitors | 吉林大学 | 2017-01-11 | — | — | CN | claimed |
| CN-105837479-A | Hydrazinonitrile cathepsin K inhibitor, and application thereof in preparation of osteoarthritis treatment drugs | 吉林大学 | 2016-08-10 | — | — | CN | claimed |
| US-9393233-B2 | Vector delivery-based microbicides | RUSH UNIVERSITY MEDICAL CENTER (US) | 2016-07-19 | — | — | US | claimed |
| US-20160095836-A1 | Vector Delivery-Based Microbicides | RUSH UNIVERSITY MEDICAL CENTER (US) | 2016-04-07 | — | — | US | claimed |
| US-9233101-B2 | — | — | 2016-01-12 | — | — | US | claimed |
| WO-1995033710-A1 | CARBAMOYL CARBOXYLIC ACID HYDRAZIDES AND THEIR USE AGAINST FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-14 | — | — | WO | claimed |
| EP-0475184-B1 | Process for the production of peptides by solid phase synthesis | HOECHST AG (DE) | 1995-02-08 | — | — | EP | claimed |
| EP-0596503-A1 | Polyurethane resins, process for producing the same, and uses thereof | SAKATA INX CORPORATION (JP) | 1994-05-11 | — | — | EP | claimed |
| WO-1993024937-A1 | TELEPHONE CABLES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-12-09 | — | — | WO | claimed |
| EP-0212808-B1 | Curable resins | TECHNOCHEMIE GMBH (DE) | 1993-11-24 | — | — | EP | claimed |
| EP-0412358-B1 | 3-AMINO-5-AMINOCARBONYL-1,2,4-TRIAZOLE DERIVATIVES | BAYER AG (DE) | 1993-09-29 | — | — | EP | claimed |
| EP-0475184-A1 | Process for the production of peptides by solid phase synthesis | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | claimed |
| EP-0141612-B1 | CURABLE BISIMIDE RESIN MIXTURES | Technochemie GmbH - Verfahrenstechnik (DE) | 1990-04-11 | — | — | EP | claimed |
| EP-0102722-B1 | MODIFIED THERMOSETTING IMIDE RESINS | The Boots Company PLC (GB) | 1986-10-01 | — | — | EP | claimed |
| US-4417021-A | POLYAMIDES, POLYHYDRAZIDES AS NUCLEATION AGENTS, MOLDING | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-11-22 | — | — | US | claimed |