Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532946 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL1409002 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL19816770 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL1408891 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL346746 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL1409041 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL7552315 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL285321 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL12006469 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL1409025 | 1.00 | PAOX (1.00) | PAOXHIF1AKDM4EMAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020069125-A1 | DEGRADERS OF HEPATITIS C VIRUS NS3/4A PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-02 | — | — | WO | disclosed |