SCHEMBL285321

SCHEMBL285321

CC(=O)NCCCCCCN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 5/20 1.00
HIF1A Q16665 2/20 0.76
KDM4E B2RXH2 1/20 0.76
MAPK1 P28482 1/20 0.76
ADRA1A P35348 1/20 0.59
SIRT6 Q8N6T7 1/20 0.51
SIRT1 Q96EB6 1/20 0.51
GNAI3 P08754 1/20 0.49
GNAO1 P09471 1/20 0.49
GNAI1 P63096 1/20 0.49
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
KDM4A O75164 1/20 0.46
TET2 Q6N021 1/20 0.46
DOHH Q9BU89 1/20 0.46
SLC6A5 Q9Y345 2/20 0.46
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31532946 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL1409002 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL19816770 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL1408891 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL346746 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL1409041 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL7552315 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL12006469 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL21842271 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A
SCHEMBL1409025 1.00 PAOX (1.00) PAOXHIF1AKDM4EMAPK1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611254-B1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF HEXAMETHYLENEDIAMINE GENOMATICA INC (US) 2023-07-05 EP claimed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 WO claimed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 EP claimed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 WO claimed
US-6462028-B2 P2Y2 AND/OR P2Y4 PURINERGIC RECEPTOR AGONISTS E.G., NUCLEOTIDES OF ADENOSINE, CYTIDINE AND URIDINE, DINUCLEOTIDES AND ANALOGS; TREATING VAGINAL DRYNESS ASSOCIATED WITH MENOPAUSE, CHEMOTHERAPY, AND DISEASES; VULVAR PAIN INSPIRE PHARMACEUTICALS, INC. 2002-10-08 US claimed
US-20020013289-A1 METHOD OF PROMOTING CERVICAL AND VAGINAL SECRETIONS MERCK SHARP & DOHME CORP. 2002-01-31 US claimed
EP-1140967-A1 TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2001-10-10 EP claimed
WO-2000039145-A1 TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2000-07-06 WO claimed
WO-1998028010-A2 USE OF MOIETIES FOR BINDING TO HYALURONAN AND ICAM-1 HYAL PHARMACEUTICAL CORPORATION (CA) 1998-07-02 WO claimed
US-20260076960-A1 METAP2 INHIBITORS AND METHODS OF TREATING OBESITY SYNDEVRX INC (US) 2026-03-19 US disclosed
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 US disclosed
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity GENOMATICA, INC. (US) 2026-03-17 US disclosed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 US disclosed
EP-0192442-A2 Detergency builder system THE PROCTER & GAMBLE COMPANY (US) 1986-08-27 EP disclosed
EP-0179408-A2 Amidoalkyl melamines and aminoalkyl melamines, and process for their preparation BASF Aktiengesellschaft (DE) 1986-04-30 EP disclosed
EP-0073267-B1 COPPER PHTHALOCYANINE BLUE REACTIVE DYES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE FOR DYEING CELLULOSIC FIBERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-03-20 EP disclosed
US-4396549-A Copper phthalocyanine blue reactive dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-08-02 US disclosed
US-4131685-A ADRENERGIC BLOCKING AGENT, CARDIAC STIMULANT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-12-26 US disclosed
US-4069254-A INHIBITORS OF BLOOD PLATELET AGGREGATION BANYU PHARMACEUTICAL CO., LTD. (JA) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity ACADM, ALDH7A1, ADSL PAOX 471/4885HIF1A 1689/4885KDM4E 543/4885
US-20260076960-A1 METAP2 INHIBITORS AND METHODS OF TREATING OBESITY METAP2, METAP1, LNPEP PAOX 1744/4885HIF1A 3764/4885KDM4E 2804/4885
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 PAOX 1178/4885HIF1A 923/4885KDM4E 1463/4885
US-12577591-B2 Microorganisms and methods for increasing co-factors ABAT, HADHB, MMAB PAOX 306/4885HIF1A 2523/4885KDM4E 2135/4885
US-20020013289-A1 METHOD OF PROMOTING CERVICAL AND VAGINAL SECRETIONS P2RY4, P2RY2, P2RY1 PAOX 1741/4885HIF1A 3377/4885KDM4E 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.