Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 16/20 | 0.49 |
| ▸ | PIM1 | P11309 | 13/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 9/20 | 0.49 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185217 | 1.00 | PIM2 (0.49) | PIM2PIM1PIM3SSTR2SSTR4 | |
| SCHEMBL2184956 | 0.91 | PIM1 (0.49) | PIM2PIM1PIM3SSTR2SSTR4 | |
| SCHEMBL2184958 | 0.91 | PIM1 (0.49) | PIM2PIM1PIM3SSTR2SSTR4 | |
| SCHEMBL2185190 | 0.86 | PIM1 (0.50) | PIM2PIM1PIM3KCNH2PIK3CA | |
| SCHEMBL2185185 | 0.86 | PIM1 (0.50) | PIM2PIM1PIM3KCNH2PIK3CA | |
| SCHEMBL2184916 | 0.84 | PIM2 (0.42) | PIM2PIM1PIM3SSTR2SSTR4 | |
| SCHEMBL12391074 | 0.80 | PIM2 (0.53) | PIM2PIM1PIM3KCNH2 | |
| SCHEMBL2184907 | 0.80 | PIM2 (0.53) | PIM2PIM1PIM3KCNH2 | |
| SCHEMBL2184908 | 0.80 | PIM2 (0.53) | PIM2PIM1PIM3KCNH2 | |
| SCHEMBL2186093 | 0.78 | PIM1 (0.48) | PIM2PIM1PIM3KCNH2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342190-A1 | BICYCLIC KINASE INHIBITORS | Novartis AG (CH) | 2011-07-13 | — | — | EP | claimed |
| WO-2010026121-A1 | BICYCLIC KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-03-11 | — | — | WO | claimed |