SCHEMBL2184369

SCHEMBL2184369

CCCCCCCC/C=C\CCCCCCCCP(=O)(OC)OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.60
MAPT P10636 3/20 0.60
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
ALDH1A1 P00352 1/20 0.60
PLA2G4A P47712 1/20 0.60
PAFAH1B2 P68402 1/20 0.60
MGLL Q99685 1/20 0.60
ABHD6 Q9BV23 1/20 0.60
TRPV1 Q8NER1 1/20 0.50
LPAR3 Q9UBY5 2/20 0.49
LPAR1 Q92633 1/20 0.47
LPAR2 Q9HBW0 1/20 0.47
GGPS1 O95749 1/20 0.44
TERT O14746 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
BLM P54132 2/20 0.44
HSD17B10 Q99714 2/20 0.44
FABP4 P15090 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184370 1.00 FAAH (0.60) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL3979768 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL2576779 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL9079352 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL1725939 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL2573332 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL5035905 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL588839 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL2184536 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1
SCHEMBL2576370 0.88 FAAH (0.61) FAAHMAPTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343355-B1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2016-12-07 EP disclosed
EP-1544279-B1 LUBRICATING COMPOSITION NIPPON OIL CORP (JP) 2016-09-28 EP disclosed
EP-1686167-B1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2016-05-25 EP disclosed
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
CN-1886490-B Lubricating oil additive and lubricating oil composition NIPPON OIL CORP 2011-04-27 CN disclosed
US-7696137-B2 Lubricating oil compositions NIPPON OIL CORPORATION (JP) 2010-04-13 US disclosed
CN-1886490-A Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2006-12-27 CN disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed
US-20050143266-A1 Lubricating oil compositions NIPPON OIL CORPORATION 2005-06-30 US disclosed
EP-1544279-A1 LUBRICATING COMPOSITION Nippon Oil Corporation (JP) 2005-06-22 EP disclosed
US-5646098-A Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives EXXON CHEMICAL PATENTS INC (US) 1997-07-08 US disclosed
US-5550241-A Adducts of cyclic carbonyl monomers and substituted alkens EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-08-27 US disclosed
EP-0510633-A1 Lubricating oil composition and use thereof JAPAN SUN OIL COMPANY, LTD. (JP) 1992-10-28 EP disclosed