Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.49 |
| ▸ | TNF | P01375 | 3/20 | 0.49 |
| ▸ | IL1B | P01584 | 3/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24440131 | 0.86 | CRBN (0.55) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL3965614 | 0.78 | CRBN (0.47) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL24317377 | 0.77 | CRBN (0.40) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL24072775 | 0.77 | CRBN (0.53) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL411067 | 0.74 | CRBN (0.53) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL24334140 | 0.74 | CRBN (0.53) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL12195990 | 0.74 | CRBN (0.53) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL2010576 | 0.73 | CRBN (0.48) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL10192664 | 0.72 | CRBN (0.53) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL10192652 | 0.72 | CRBN (0.53) | CRBNDDB1TNFIL1BIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3622960-A1 | NATURAL KILLER CELLS FROM PLACENTA | Celularity, Inc. (US) | 2020-03-18 | — | — | EP | disclosed |