SCHEMBL2184469

SCHEMBL2184469

CCCCCCC=CNC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.50
TRPV1 Q8NER1 1/20 0.50
TSHR P16473 2/20 0.44
TERT O14746 3/20 0.43
PTPN1 P18031 3/20 0.43
CYP1A2 P05177 2/20 0.43
MAPT P10636 2/20 0.43
CYP2C19 P33261 2/20 0.43
BLM P54132 2/20 0.43
HSD17B10 Q99714 2/20 0.43
FABP4 P15090 2/20 0.43
PPARG P37231 2/20 0.43
KMT2A Q03164 2/20 0.43
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
GMNN O75496 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184551 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2184550 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2184493 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL8021133 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2184489 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2184662 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL2184657 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL386661 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL22215593 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL387901 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3798214-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2021-03-31 EP disclosed
CN-102268317-B Lubricating oil additive, lubricating oil composition containing the same, and process for producing the same NIPPON OIL CORP 2013-09-18 CN disclosed
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
CN-1671828-B Lubricating oil additives, lubricating oil compositions containing such additives, and methods for producing such additives and compositions NIPPON OIL CORP 2012-05-30 CN disclosed
CN-102268317-A Lubricating oil additive, lubricating oil composition containing the same, and process for producing the same 2011-12-07 CN disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
CN-1886490-B Lubricating oil additive and lubricating oil composition NIPPON OIL CORP 2011-04-27 CN disclosed
US-7732385-B2 Lubricating oil additives, lubricating oil compositions containing such additives and processes for producing such additives and compositions NIPPON OIL CORPORATION (JP) 2010-06-08 US disclosed
CN-1886490-A Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2006-12-27 CN disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed
CN-1671828-A Lubricating oil additives, lubricating oil compositions containing such additives, and methods for producing such additives and compositions NIPPON OIL CORP (JP) 2005-09-21 CN disclosed
US-20050113265-A1 Lubricating oil additives, lubricating oil compositions containing such additives and processes for producing such additives and compositions NIPPON OIL CORPORATION 2005-05-26 US disclosed
EP-1516911-A1 LUBRICATING OIL ADDITIVE, LUBRICATING OIL COMPOSITION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME Nippon Oil Corporation (JP) 2005-03-23 EP disclosed