Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 15/20 | 0.54 |
| ▸ | MAOB | P27338 | 15/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520647 | 0.80 | ALOX15 (0.68) | MAOAMAOBALOX15TSHRHSD17B10 | |
| SCHEMBL21845116 | 0.79 | PARP11 (0.47) | — | |
| SCHEMBL21845054 | 0.78 | AOC3 (0.49) | — | |
| SCHEMBL21845102 | 0.77 | AOC3 (0.70) | MAOAMAOB | |
| SCHEMBL7399814 | 0.76 | MAOB (0.57) | MAOAMAOBALOX15TSHRHSD17B10 | |
| SCHEMBL17703887 | 0.74 | MAOB (0.67) | MAOAMAOBHRH3 | |
| SCHEMBL13532003 | 0.74 | MAOB (0.66) | MAOAMAOBHRH3 | |
| SCHEMBL31711410 | 0.74 | HSD17B10 (0.62) | MAOAMAOBALOX15TSHRHSD17B10 | |
| SCHEMBL6825249 | 0.74 | MAOB (0.66) | MAOAMAOBHRH3 | |
| SCHEMBL7389120 | 0.74 | HSD17B10 (0.62) | MAOAMAOBALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087248-A1 | Fluoroallylamine Derivative And Use Thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087248-A1 | Fluoroallylamine Derivative And Use Thereof | VAPB, VAPA, SLC28A1 | MAOA 25/4885MAOB 60/4885ALOX15 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.