Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 11/20 | 0.36 |
| ▸ | CDK2 | P24941 | 11/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21845550 | 0.76 | LIMK1 (0.44) | UCHL1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL17632008 | 0.75 | UCHL1 (0.44) | CCNE1CDK2CDK5CDK5R1UCHL1 | |
| SCHEMBL17644063 | 0.75 | UCHL1 (0.44) | CCNE1CDK2CDK5CDK5R1UCHL1 | |
| SCHEMBL21845491 | 0.73 | USP30 (0.51) | CCNE1CDK2CDK5UCHL1CNR2 | |
| SCHEMBL20877325 | 0.73 | UCHL1 (0.45) | CCNE1CDK2CDK5CDK5R1UCHL1 | |
| SCHEMBL20877327 | 0.73 | UCHL1 (0.45) | CCNE1CDK2CDK5CDK5R1UCHL1 | |
| SCHEMBL21283661 | 0.73 | CDK2 (0.46) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL22522760 | 0.71 | CCNE1 (0.52) | CCNE1CDK2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL20883057 | 0.71 | UCHL1 (0.44) | CCNE1CDK2CDK5CDK5R1UCHL1 | |
| SCHEMBL20883082 | 0.71 | UCHL1 (0.44) | CCNE1CDK2CDK5CDK5R1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-B1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2020-03-18 | — | — | EP | disclosed |