Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24037116 | 0.95 | PRSS1 (0.53) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL15004143 | 0.84 | PRSS1 (0.62) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL19791258 | 0.84 | PRSS1 (0.62) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL23568075 | 0.84 | PRSS1 (0.49) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL19871610 | 0.84 | PRSS1 (0.62) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL21599352 | 0.81 | WDR5 (0.59) | PRSS1PRSS2PRSS3WDR5GRIN2B | |
| SCHEMBL24747308 | 0.81 | PRSS1 (0.59) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL21707252 | 0.81 | PRSS1 (0.59) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL22271165 | 0.80 | WDR5 (0.57) | PRSS1PRSS2PRSS3WDR5GRIN2B | |
| SCHEMBL19791251 | 0.80 | WDR5 (0.57) | PRSS1PRSS2PRSS3WDR5GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627730-B1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |
| EP-2748878-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |